5 results
The purpose of the study is to investigate the optimal dose combination of both drugs in healthy volunteers who will undergo a pain test.
Primary objectiveThe primary objective is to evaluate the effectiveness, safety, and tolerability of increasing doses of tapentadol PR (300 mg per day after run in, up titration to 500 mg per day) versus a combination of tapentadol PR (300 mg per…
Primary Objective:* To determine the efficacy of silver impregnated dressings compared to a topical antibiotic to treat patients with PEG-site infections.Secondary Objectives:* To investigate the reduction and or change in stomal bacterial profile…
The purpose of this study is to assess the safety, tolerability and efficacy of long term drisapersen in subjects with DMD.
PRIMARY: Dose finding part (Phase 1):To assess the safety and tolerability of durvalumab when given in combination with lenalidomide and rituximab; ibrutinib; or bendamustine and rituximab to determine the recommended Phase 2 doses (RP2Ds) of each…