5 results
The aim of this study is to evaluate the safety and feasibility of postoperative pericardial perfusion with (prewarmed NaCl 0.9%) and the effect of perfusion on blood loss after cardiac surgery. Hypothesis Pericardial perfusion with (prewarmed NaCl…
Objectives of the randomized controlled trialPrimary objective: To determine whether postoperative pericardial flush with a crystalloid can reduce postoperative blood loss by effectively removing contaminated pericardial blood after CABG. The…
Primary objective: To determine whether postoperative pericardial flush with a crystalloid can reduce postoperative blood loss by effectively removing contaminated pericardial blood after valvular surgery and correction for CHD. The primary…
Primary ObjectiveThe primary objective is to assess safety and tolerability, describe the dose limiting toxicities (DLTs), and determine the maximum tolerated dose (MTD) or the maximum administered dose (MAD; in the absence of exceeding the MTD) for…
Part 1: To evaluate the efficacy and safety of imetelstat in transfusion dependent subjects with low or intermediate-1 risk MDS that is relapsed/refractory to ESA treatment.Part 2: To compare the efficacy, in terms of red blood cell (RBC)…