3 results
The objective of this study is to demonstrate superior efficacy and evaluate the safety of MACI Implant compared with arthroscopic microfracture in the treatment of patients (aged 18 to 55 years old) with symptomatic articular cartilage defects of…
Primary Objective* To evaluate the efficacy of VX-561Secondary Objectives* To evaluate the pharmacodynamic (PD) effect of VX-561* To evaluate the pharmacokinetics (PK) of VX-561, IVA, and relevant metabolites* To evaluate the safety and tolerability…
Primary ObjectivesParts 1 (Subjects with F/MF genotypes) and 2 (Optional; Subjects with the F/F genotype)* To evaluate the safety and tolerability of VX 121 in TC with TEZ/VX 561 (deuterated IVA) * To evaluate the efficacy of VX 121 in TC with TEZ/…