6 results
Primary Objective:The primary objective is to evaluate the efficacy of repeated once-daily doses of odevixibat versus placebo in children with biliary atresia (BA) post Kasai hepatoportoenterostomy(HPE) based native liver survival (NLS) of up to 104…
To demonstrate a sustained effect of odevixibat on pruritus in patients with ALGS who have completed study A4250-012 (ASSERT)
The primary objective of this study is to investigate the accuracy and reliability of ultrasound scoliosis measurements and progression of the curve and to correlate these outcomes with the standard radiographic measurements obtained at the same…
Primary Objective:To demonstrate the efficacy of repeated daily doses of 120 µg/kg/day odevixibat in relieving pruritus in patients with ALGS.Secondary Objectives:To assess the impact of odevixibat on serum bile acid levels in patients with ALGS.To…
Primary objective: • To assess the pharmacokinetics of DOR in patients prior to and after BSSecondary objectives: • To assess the safety of DOR in patients prior to and after undergoing BS• To assess the viral response to DOR in patients prior to…
Primary Objective: the primary objective of this study is to investigate the accuracy and reliability of coronal curve ultrasound measurements in patients with scoliosis as well as the accuracy and reliability of ultrasound imaging to detect…