5 results
We aim to investigate whether this damage results from altered pulmonary blood flow patterns and related increases in shear stress and vascular remodelling. To test our hypothesis we will make use of novel techniques to quantify pulmonary perfusion…
Quizartinib selectively inhibits survival pathways that block apoptosis by inhibiting FLT3. Quizartinib inhibits proliferation of FLT3-dependent cell lines, and is effective in human leukemia tumor xenograft models of AML. Data from the Phase 1 and…
Primary objective To investigate the safety and tolerability of CCS1477 as monotherapy and in combination.
To compare progression free survival (PFS) between treatment with docetaxel or cabazitaxel and darolutamide versus treatment with docetaxel or cabazitaxel in mCRPC patients.
To determine the influence of darolutamide on the pharmacokinetics of cabazitaxel compared to cabazitaxel alone in mCRPC patients.