3 results
The primary objective will be to assess the safety and tolerability of this combination and to determine whether the MTD ofEMD 521873 is reached up to a dose of 0.45 mg/kg. Secondary objectives will be the evaluation of the PK, immunogenicity,…
Objectives: To test the hypothesis that the thyroid gland of offspring of long-lived siblings is more resistant to stimulation with TSH compared to the thyroid gland of their partners, offspring and partners will receive a low dose of recombinant…
The primary objective of this study is to evaluate the effectiveness of two differently sized pistons used in primary stapedotomy for otosclerosis in terms of hearing improvement, complication rate and general and disease-specific quality of life.