12 results
Primary: To demonstrate the efficacy of QGE031 relative to placebo at 12 weeks in patients withatopic dermatitis (AD) as assessed by Eczema Area and Severity Index (EASI).Secondary: efficacy assessed by Investigator Global Assessment (IGA, 12 weeks…
This study is designed to demonstrate equal therapeutic effect of Myfortic® as compared to MMF in this patient group, thus improving therapeutic efficacy.
Primary Objective: To study whether the pulse oximeter functionality of the wearable ear sensor is able to reliably measure oxygen saturation, pulse rate, and respiratory rate in a clinical (postoperative) setting.Secondary Objective(s): To evaluate…
To assess the safety, tolerability, pharmacodynamics and efficacy of two DLQ02 topical formulations in patients with plaque psoriasis. To assess systemic exposure of CsA and F6H8 after topical application.
To evaluate the long-term safety and tolerability of elexacaftor(ELX)/tezacaftor (TEZ)/ivacaftor (IVA)
The main objective of this study is to validate the accuracy of the device to monitor the physical activity of a subject by comparing the measured values to the golden standard (video recording).
To evaluate the effect of elexacaftor (ELX)/tezacaftor (TEZ)/ivacaftor (IVA) on glucose tolerance in CF subjects with impaired glucose tolerance (IGT) or CF related diabetes (CFRD)
Primair eindpunt:Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy in Subjects With Cystic Fibrosis (CF) Who Are Homozygous or Heterozygous for the F508del Mutation.Secundair eindpunt:Evaluate the long-term efficacy of VX-…
The main objectives of this study are to determine the accuracy of the device (1) to determine functional oxygen saturation (SpO2) compared to a reference device, and (2) to determine respiratory rate compared to visual observations. As a secondary…
To evaluate the efficacy of VX-121/TEZ/D-IVA in CF subjects who are homozygous forF508del, heterozygous for F508del and a gating (F/G) or residual function (F/RF) mutation, orhave at least 1 other TCR CFTR mutation and no F508del mutation
To evaluate the efficacy and pharmacodynamics (PD) of ELX/TEZ/IVA
To assess the concurrent validity of the FastFocus* Vital Sign Monitoring System classification algorithm that discriminates between lying, sitting/standing, and walking activities, and detects number of walking steps in hospitalised patients under…