3 results
Approved WMOCompleted
1. What is the effect of a clinical oral dose of acetazolamide on the isocapnic hypoxic response (IHR), i.e. an exposure to hypoxia (end-tidal PO2 ~ 5.8 kPa) during 30 min? Does the agent increase the IHR as would be expected from the state of…
Approved WMOCompleted
To ascertain whether the survival time distribution for patients randomized to the investigational arm is consistent with longer survival as compared to patients randomized to the control arm.
Approved WMORecruiting
To investigate whether on demand dosing using population-based PK-models in VWD patients is reliable and feasible.