6 results
The primary objective of the study is to determine concentration of circulation cytokines na administration of LPS in the presence of iron sucrose (Venofer®), Deferasirox (Exjade®) of placebo.
Use of iron chelation therapy has demonstrated benefits in terms of morbidity and mortality for chronically-transfused thalassemia patients with iron overload. Recent retrospective data (Leitch 2007, Rose 2010, Sanz 2008) suggest that overall…
To examine the effects of mono- and combination therapy with linagliptin and empagliflozine on renal hemodynamics
To gain more knowledge about the effects of SGLT2 inhibition on renal hemodynamics and the underlying mechanisms.
The study investigates whether the glycemic response to standardized snacks differs within subjects between different times of the day. The study concerns a pilot for a future larger study of more complex aspects of the nutritional and physical…
To study the safety and efficacy of deferasirox as treatment of oxidative stress in adult subjects with sickle cell disease.