6 results
Primary Objective* To evaluate the antitumor efficacy of PO single agent CO-1686, as measured by ORR, when administered to patients with EGFR mutated, centrally confirmed T790M positive and T790M negative advanced NSCLC after tumor progression on 1…
Primary Objective:• To investigate the efficacy of KVD900 compared to placebo in halting the progression of a peripheral or abdominal attack of hereditary angioedema (HAE).Secondary Objectives:• To investigate the safety and tolerability of KVD900…
The primary objective of the study is to assess whether ultrasound-facilitated, catheter-directed, thrombolysis and anticoagulation are associated with a significant reduction in the composite outcome of PE-related mortality, cardiorespiratory…
Primary Objective: To demonstrate the clinical efficacy of KVD900 compared with placebo for the on-demand treatment of HAE attacks.Secondary Objective: To investigate the safety and tolerability of KVD900.
The primary aim of the study is to evaluate whether treatment with the EKOS device on top of anticoagulation in patients with severe pulmonary embolism results in a better clinical outcome than treatment with anticoagulation alone. The primary…
Primary Objective: To assess the safety of long-term administration of KVD900 in adolescent and adult patients with HAE type I or II.Secondary Objectives: • To assess the long-term efficacy of KVD900 in the treatment of attacks in adolescent and…