5 results
Primary objectives:Phase 1b:Arm A (BGB-290 + radiation therapy [RT]): Subjects with first-line glioblastoma (GB) with unmethylated MGMT promoter (*unmethylated GB*)• To assess safety and tolerability of BGB-290 combined with RT• To identify dose-…
Primairy objective:• To determine the safety, tolerability and pharmacokinetics of 2B3-201, and in comparison to free methylprednisolone hemisuccinate and placebo;Secundairy objective:• To determine the pharmacodynamic effects of 2B3-201 on CNS…
Part I (cross-sectional study)1. To identify breathprints of VOCs by electronic nose in exhaled air that are associated with a bacterial origin of an exacerbation in COPD patients. 2. To examine the critical VOCs of these breathprints in exhaled air…
The overall aim of this study is to assess the frequency, patient-reported severity and impact of cough, and the distribution of coughing fits during the daytime and nighttime, in a population of patients with non-IPF ILDs.Primary objective: The…
The overall aim of the study is to develop innovative minimally invasive monitoring techniques that can identify lung inflammation in pwCF when using highly effective modulators, compared to patients whom are not eligible for CFTR modulators (…