12 results
The purpose of this study is to determine whether LCQ908 is effective and safe in lowering triglycerides in subjects with FCS (HLP type I).
We propose to conduct a study in healthy young and elderly subjects and patients diagnosed with mild to moderate AD, FTLD, or DLB where cholinergic and serotonergic challenges are given in a placebo-controlled, crossover fashion. Before each…
To examnine the effectiveness of psychological interventions and psychopharmacological interventions compared to placebo-control.
Do high plasma free fatty acids lower central serotonergic responsivity?
The objective of this study is to assess the effects of an increased NE level on the trade-off between exploitation and exploration. More specifically, this study will compare the exploitative/explorative behavior of participants who received either…
The primary objective is to examine whether a combined treatment with rivastigmine (cholinesterase inhibitor) and citalopram (selective serotonin re-uptake inhibitor) will improve memory as compared to the treatment with either rivastigmine or…
Part I (cross-sectional study)1. To identify breathprints of VOCs by electronic nose in exhaled air that are associated with a bacterial origin of an exacerbation in COPD patients. 2. To examine the critical VOCs of these breathprints in exhaled air…
To examine in depressed patients who reach a stable depression remission during optimal AD treatment: 1) whether discontinuation is possible; 2) when discontinuation is possible; and 3) in whom discontinuation is possible.
To assess the effect of citalopram on chest pain in patients with achalasia and to evaluate the effect of citalopram on esophageal sensitivity.
The overall aim of the study is to develop innovative minimally invasive monitoring techniques that can identify lung inflammation in pwCF when using highly effective modulators, compared to patients whom are not eligible for CFTR modulators (…
To assess the effect of citalopram on symptoms of chest pain in patients with functional chest pain.
The overall aim of this study is to assess the frequency, patient-reported severity and impact of cough, and the distribution of coughing fits during the daytime and nighttime, in a population of patients with non-IPF ILDs.Primary objective: The…