5 results
To determine the toxicity of adding chloroquine in escalating doses in patients with small cell lung cancer to standard therapy.
To determine the toxicity of adding chloroquine in escalating doses in patients with small cell lung cancer to standard therapy.
Primary objective * To determine the maximum tolerated dose and recommended dose of metformin plus chloroquine in patients with IDH1/2MT glioma, IHCC and CS Secondary objectives * To describe the toxic effects of metformin plus chloroquine in…
Primary Objective:Evaluating the predictive value of CAUS to assess the steatosis severity, combining multiple CAUS parameters (RAC, LAT, SNR, MU, AX), with 1H-MRS as a reference in adult patients with CIF.Secondary Objective(s):-To assess the…
Primary objective• To determine the MTD/RPTD for CQ in combination with concurrent radiotherapy with daily TMZ in patients with a newly diagnosed GBM.Secondary objectives• To characterize the safety and tolerability of CQ in combination with…