9 results
Primary objective: The primary objective of the study is to determine the effect of oral dipyridamole treatment on the innate immune response induced by a lipopolysaccharide (LPS) challenge. Various pro- and anti-inflammatory cytokines will be…
Determine whether phenylephrine or norepinephrine has superior haemodynamical effects in ophtalmic surgery
The primary objective of the study is to determine concentration of circulation cytokines na administration of LPS in the presence of iron sucrose (Venofer®), Deferasirox (Exjade®) of placebo.
To investigate the hypothesis that in women with a multiple pregnancy prophylactic use of a pessary will be effective in the prevention of preterm delivery and the neonatal mortality and morbidity resulting from preterm delivery. To assess in women…
To evaluate the safety and efficacy of long term stimulation of the lower esophageal sphincter in patients with gastroesophageal reflux disease after sleeve gastrectomy.
The primary safety objective of this investigation is to assess the safety of long-term LES electrical stimulation therapy in patients with GERD.The primary functionality objective of this study is to evaluate the ability of the device to initiate…
Does antagonism of the adenosine receptor by caffeine lead to an increased LPS-induced inflammatory reaction and an increase in (subclinical) tissuedamage?Does the C34T-polymorphism of the enzyme AMP-deaminase lead to a decreased inflammatory…
To compare the effectiveness of progesterone and cervical pessary in the prevention of preterm birth in women with singleton and twin pregnancies and a short cervix.
The objective of this study is to evaluate the (cost-)effectiveness of reduced noradrenaline in patients with CS by using a lower MAP target of >= 55 mmHg, compared to usual care. We hypothesize that reduced use of noradrenaline will improve…