5 results
The primary objective of this trial is to describe the safety and tolerability of prolonged exposure to cebranopadol in subjects suffering from cancer related pain
To assess the analgesic efficacy, safety, and tolerability of once daily orally administered cebranopadol in a total of 3 fixed doses (100 µg, 300 µg, and 600 µg cebranopadol) compared to placebo in subjects with moderate to severe chronic pain due…
To assess the accuracy of the screw placements after using a surgical guide in patients operated for intra-articular tibial fractures.
To assess the accuracy of the screw placements after using a surgical guide in patients operated for acetabular fractures. This study will learn us which screws benefit (in accuracy of the placement) from using a surgical guide.
Primary • To evaluate the effects of cebranopadol and oxycodone on respiratory drive.Secondary• To evaluate the pupil response/ pupillometry following single oral doses of cebranopadol and oxycodone• To evaluate the effects of single oral doses of…