5 results
Specific Aim #1: To evaluate the efficacy and safety of shortened-duration (6 weeks total) versus conventional duration (3 months total) anticoagulation for first-episode, provoked, acute venous thrombosis among children in whom thrombus resolution/…
The primary objective of this study is to evaluate efficacy and safety. Secondary objectives: PK, PK-PD.
Objectives1. to determine whether nebulization of heparin decreases coagulation activation in the pulmonary compartment (i.e. BAL fluid)2. to determine whether nebulization of heparin decreases pulmonary vascular permeability
The objective op this study is to answer the following questions:-Is thrombin generation increased after abrupt cessation of intravenous unfractionated heparin after discontinuation of CVVH?-Is there a difference in increase in thrombin generation…
To characterize the single-dose pharmacokinetic (PK) of RPV after SC administration of RPV LA suspensions with different doses and/or different particle size (PS) to support further dose and formulation selection, in healthy adult participants.To…