6 results
The primary endopoint is to determine whether ketoconazole/octreotide combination therapy, followed by octreotide monotherapy, is an effective treatment for Cushing's disease. Secundary endpoints address the effects of this therapy on bone…
The objective of the study is to improve medical treatment of Cushing's disease by combining partially independent medical therapies which act through differential mechanisms. Given the high affinity of SOM230 to sst5 and considering the facts…
To replicate and extend the findings of the recent methylphenidate study in which methylphenidate was found to enhance episodic memory performance; To explore whether this effect of methylphenidate is primarily mediated by its dopaminergic action.
The aim of the feasibility study is to test the home hospitalisation platform (care pathway empowered by the integrated home hospitalisation platform) through small scale pilots in three different hospitals: Isala, Jessa hospital and Maastricht UMC…
To assess the prevalence of QT-prolongation in patients who are prescribed domperidone as part of usual care, and to assess potential risk factors for that QT-prolongation.
The purpose of this study, is to evaluate the efficacy and safety of pasireotide alone or in combination with cabergoline in patients with Cushing*s disease as measured by the proportion of patients achieving normal UFC at the end of the study…