5 results
Primary: Long-term safety and tolerability.Secondary: Long-term efficacy.
Primary: To evaluate the efficacy of retigabine as adjunctive therapy to each of the following specified monotherapy AED treatments: carbamazepine/ oxcarbazepine, lamotrigine, levetiracetam or valproic acid in subjects with partial-onset seizures (…
Patients with ALS are routinely prescribed riluzole, the only registered drug for the treatment of ALS. This study will evaluate the concentration-effect relationship of riluzole (100 mg) and retigabine (300 mg) on axonal excitability measures. In…
The aim of this study is to investigate whether a mobile telemonitoring guided CR (mCR) as alternative for a regular CR programme is an effective means to increase participation and adherence of elderly in a CR programme, and results in better long…
1. To evaluate the feasibility of cryoballoon therapy in patients with incurable esophageal carcinoma and symptoms of dysphagia, defined as technical success rate. In addition, the efficacy and safety will be assessed by looking at the clinical…