3 results
Approved WMOCompleted
To gain insight into the full spectrum of temperature-induced changes in glucose homeostasis, the present study will be aimed at assessing the effect of acute whole-body heat exposure on liver insulin sensitivity, substrate oxidation and plasma…
Approved WMOCompleted
To investigate the possibility to measure non-invasively perfusion and oxygenation in static physiological conditions in the lower leg using MSOT.
Approved WMOCompleted
To characterize the safety, tolerability, and recommended phase 2 dose (RP2D) of each combination partner used with ruxolitinib (Part 1)To evaluate the preliminary efficacy of each novel ruxolitinib combination treatment arm (Parts 2 & 3)