5 results
Demonstrate that the usage of a quadripolar LV lead results in easier LV lead implantation procedure and less chronic LV lead related adverse events in comparison with a traditional biventricular left ventricle lead.
To establish the MTD and/or recommended phase II dose of the coadministration of LDE225 and INC424 in patients with MF, who have not previously received therapy with a JAK inhibitor
The Purpose of the study is to investigate the clinical feasibility of the TW15 and TW22.
The primary objective is to investigate the safety and efficacy of LDE225 with respect to overall response rate according to independent central review (ICR).The key secondary objective is to assess LDE225 with respect to progression-free survival (…
The hypothesis is that personalised and risk-adapted treatment will improve outcome and reduce toxicity in post-pubertal patients with medulloblastoma.A further hypothesis is that clinical, magnetic resonance imaging (MRI) and voxel-based…