5 results
The purpose of the study is to investigate how safe the compound is and how well the compound is tolerated when it is applied in the form of transdermal patches. The study will also investigate how quickly and to what extent bisoprolol is absorbed…
The main question of this study is: *Is selective beta-blocker treatment safe and effective in reducing sympathetic overdrive, thereby improving RV function and remodeling in patients with iPAH?*.In addition to the determination of RVEF, we will…
To assess whether tianeptine is able to antagonize opioid-induced respiratory depression.
This is a mechanistic exploratory study. The objective of this study is to determine the effects of PulseCath® iVAC2L on ventricular loading conditions and assess impact on specific load and flow dependent humoral factors as well as cardiac enzymes…
Here we will perform a proof of concept study on the ability of the antidepressant tianeptine to prevent respiratory depression from the opioid alfentanil in humans.