5 results
What is the correlation between change in Mannitol PD15 (provoking dose of mannitol to cause a >= 15% fall in FEV1 ) 6h after a single dose of beclomethasone and after 4 weeks of treatment with beclomethasone?
1. To investigate the safety and tolerability of single oral doses of NS11821 in healthy male subjects and estimate a maximum tolerated dose.2. To investigate the pharmacokinetics (PK) of single ascending oral doses of NS11821.
To compare the methods patients will be divided into two groups, a therapy group (receiving cTreatment) and a control group (receiving standard cryotherapy). Patients will be evaluated pre- and postoperatively, wherefore the following data are…
Protocol version Amendment 1, 31-Jul-2015, paragraph 2.1, page 28:Primary objective:The primary objective is to assess the effect of tirasemtiv versus placebo on respiratory function in patients with ALS.Secondary objectives:* Evaluation of…
The primary objective is to assess the long-term safety and tolerability of tirasemtiv, inpatients with ALS