9 results
The study is designed to clinically demonstrate device acute safety (Primary Endpoint) along with longer FU device safety and effectiveness evaluation (Secondary Endpoint).The main objectives of the study areU :1) Evaluate the Acute safety of the…
To explore the dose-response relationship between supplemental oxygen and sublingual microcirculatory perfusion and hemodynamics in healthy volunteers
1. To study the effect of different target PaO2's on myocardial damage, hemodynamics, microcirculation and organ perfusion in CABG patients.2. To study underlying mechanisms of hyperoxia by determining differences in oxidative stress response…
To find the optimal dose of neladenoson bialanate for the Phase III trial by detecting and characterizing a significant dose-response relationship in the two primary efficacy endpoints, absolute change from baseline in LVEF and log-transformed NT-…
To assess the benefits and harms of two targets of partial pressure of oxygen in arterial blood (PaO2) in guiding the oxygen administration in acutely ill adults with hypoxaemic respiratory failure at ICU admission.
1. To study the short- and long-term effect of different target PaO2's on circulatory status, organ dysfunction and outcome.2. To study underlying mechanisms of hyperoxia by determining differences in oxidative stress response between the…
To investigate the effect of maternal hyperoxygenation with 100% in the second stage of labor and in the presence of abnormal fetal heart rate (FHR) patterns on fetal condition, instrumental delivery rate and free radical production. In case a…
To assess clinical improvement of skin severity in patients with ichthyosis
To assess whether HBOT reduces pain, and improves physical functioning and QoL in breast cancer patients with late radiation toxicity.