10 results
Goal of this study is to assess the feasibility of a biodegradable polyurethane foam for closing of oroantral communications with a few modifications compared to the first pilot study. The assessment will take place in a small number of patients. On…
Goal of this study is to asses the feasibility of polyurethane foam as a local hemostatic agents in sockets after dental extraction. The assessment will take place in a small number of patients. After the pilot study, a large study will be…
Goal of this study is to assess the feasibility of a biodegradable polyurethane foam for closing of oroantral communications. The assessment will take place in a small number of patients. On the long term, the objective is the clinical appliance of…
Goal of this study is to assess the treatment of OACs with biodegradable polyurethane foam, as carried out in the pilot studies, in a large number of patients.
Objectives:Primary Objective: to investigate the anti-tumor efficacy of domatinostat in combination with avelumab in advanced unresectable/metastatic MCC patients progressing on anti-PD-(L)1 antibody monotherapy.Secondary Objectives: to investigate…
To demonstrate superiority with regard to Progression Free Survival based on an Independent Review Committeeassessment of avelumab versus platinum-based doublet in NSCLC subjects with PD-L1+
The primary objective of the present study is to examine the orthotic and therapeutic effect of the ironHand (iH) system, consisting of both an assistive and therapeutic module, by elderly and diagnosed patients with hand function problems, after…
The primary objective of this study is to explore user acceptance of the ironHand (iH) system by elderly. Secondary objectives are to examine the direct effect on functional task performance, changes in hand strength and movement execution of such a…
• Determine the maximum tolerated dose (MTD) and/or recommended dose (RD) for further evaluation of XL092 when administered alone and in combination with ICIs to subjects with advanced solid tumors• Evaluate preliminary efficacy of XL092 when…
Primary Objective: to evaluate clinical efficacy of domatinostat in combination with avelumab in treatment-naïve metastatic or distally recurrent MCC patients as determined by the Objective Response Rate (ORR) according to Response Evaluation…