7 results
To test the impact of the addition of axitinib to standard chemotherapy treatment on histology samples
To determine the relation between tumor tissue phosphoproteomic profiles and progression-free survival (PFS) in patients with advanced RCC
Aim of the studyIn this prospective, observational trial, we aim to investigate the accuracy, precision and concordance of VFR in patients after open abdominal aortic aneurysm (AAA) repair during their stay in the ICU. CO measurements obtained with…
Sub-study APhase 1b:To assess the DLT rate and estimate the MTD of sasanlimab in combination with encorafenib and binimetinib to determine the RP2D for the combination. Phase 2:To assess the durable ORR of sasanlimab in combination with encorafenib…
Primary ObjectiveTo demonstrate that avelumab in combination with axitinib is superior to sunitinib monotherapy in prolonging PFS or OS in the first-line treatment of PD-L1 positive patients with aRCC.Secondary Objectives* To demonstrate that…
To investigate efficacy of neoadjuvant axitinib and avelumab in patients with localized renal cell carcinoma with moderate to high risk of recurrence .
The aim of the present pilot study is to investigate whether nHFT of different settings (with different flow rates and additional amounts of oxygen) stabilizes respiration and thus improves AHI index and promotes compliance with the therapy in…