7 results
Our objective is to evaluate the patency of paclitaxel coated balloons in hemodialysis patients presenting at the radiology department more than once a year with repetitive severe stenoses of their fistula, and compare the results with primary…
Primary Objective:* The primary objective is to demonstrate the efficacy of avapritinib based on progression-free survival (PFS) determined by central radiological assessment per modified Response Evaluation Criteria in Solid Tumors (mRECIST),…
The aim of the study is to reduce depression symptoms and alcohol intake simultaneously in a population of young adults with a depressive disorder and problematic alcohol use. For this study online CBT/MI based alcohol reduction self-help add-on…
GSH CBT-E is an internet-based guided self-help intervention. Objective of this study is to investigate the effectiveness of GSH CBT-E in comparison with a waiting list condition on frequency of binge eating (BE). Secondary objective is to measure…
Primary: Part 1 • To determine the RP2D of avapritinib in patients with ISM for use in Part 2 and Part 3 of the study.Part 2 • To determine main change in ISM-SAF TSS from baseline to C7D1, compared to placebo. Part 3 • To assess the long-term…
Primary: • The primary objective is to determine adjudicated ORR (CR/CR with partial recovery of peripheral blood counts [CRh] + PR + CI) based on modified IWG-MRT-ECNM consensus response criteria in patients with AdvSM treated with avapritinib and…
This study compares the efficacy of guided self-help CBT-E with to screen-to-screen CBT-E in terms of robust remission at end of treatment and during follow up. Robust remission will be defined as eating disorder pathology below a clinical cut-off…