5 results
Investigate the value of percutaneous radiofrequency heat lesion, applied to the medial branch of the primary dorsal ramus; more specifically try to determine if a significant and long lasting pain reduction can be obtained as compared to a sham-…
investigate the value of percutaneous pulsed radiofrequency, applied to the lumbar and sacral dorsal root ganglion; more specifically try to determine if a significant and long lasting pain reduction can be obtained as compared to a sham-operated…
Primary: Progression Free Survival (PFS) in patients treated with AUY922 versus pemetrexed or docetaxel.Secondary: Overall response rate, disease control rate, overall survival, safety and tolerability, PK.
The primary objective of this study is to obtain clinical proof of principle that the addition of a PgP/BCRP inhibitor increases CNS concentrations of tyrosine kinase inhibitors by inhibition of drug efflux transporter function in the blood brain…
Investigate the value of percutaneous radiofrequency heat lesion applied to the ramus communicans; more specifically try to determine if a significant and long lasting pain reduction can be obtained as compared to a sham-operated group. In addition…