4 results
Primary objectivesTo evaluate the effect of the CYP1A2 inhibitor, fluvoxamine, on steady state pharmacokinetics of TKI258 in patients with advanced solid tumors, excluding breast cancerSecondary objectives• To characterize the safety and…
To determine whether there are clinically important beneficial effects of the addition of atropine during induction of anesthesia with propofol/remifentanil on the hemodynamic profile and on peripheral and cerebral tissue oxygenation and…
In this study we will look at how quickly and to what extent the study compound MEN1611 is absorbed, transported, and eliminated from the body (this is called pharmacokinetics) and how this is influenced by the approved drug itraconazole fluvoxamine…
The study*s primary objective is to assess the safety and tolerability of CP-506 alone or in combination therapy. The 3 different modules explore the administration of CP-506: alone (Module 1) or in combination with Carboplatin (Module 2) or in…