11 results
We would like to eludicate the role of dopamine on glucose metabolism.
To assess the analgesic effect of ARA290 in chronic pain patients
To study the effects of ARA290 on the cognitive and neural processing of emotions in healthy volunteers 7 days post-administration.
(1) To assess the effect of ARA 290 on the ventilatory response to hypoxia (and compare the effects to Epo); (2) To assess the effect of ARA 290 on the gradient over the tricuspid valve during hypoxia (and compare the effects to Epo); (3) To assess…
This is an open label proof of principle study, in 14 patients. The objective of the study is to test the efficacy and safety of ARA 290 in patients with active rheumatoid arthritis. To assess the efficacy, disease activity is examined based on…
1)To determine whether subjects at ultra high risk to develop schizophrenia display hepatic insulin resistance as compared to healthy controls matched for age, sex, BMI, ethnicity, visceral and subcutaneous fat mass.2)To determine whether…
ARA290 is a new drug against neuropathic pain and was succesfully tested in previous studies on patients with neuropathic pain due to diabetes and sarcoidosis. The current study involves sarcoidosis patients with pain due to neuropathy. The purpose…
In this study we will assess the effect of ARA290 on nerve damage by taking 4 skin bipsies during treatment.
To measure the PK of ARA290 when given in de SQ form
To measure the plasma conc. of ARA 290 in healthy volunteers
The main objective of the present study is to compare the clinical outcome of bone marrow stimulation alone versus bone marrow stimulation and bone marrow aspirate concentrate (BMAC) for small symptomatic osteochondral defects of the talus.