6 results
This study will evaluate the effectiveness of DRG neurostimulation for treating chronic groin pain and capture pilot data regarding the mechanisms of DRG neurostimulation.
Primary ObjectiveTo determine the influence of treatment for OSA opioid-induced respiratory depression (minute ventilation (Vi); tidal volume (Vt); respiratory rate (RR); end-tidal pCO2; SpO2).Secondary ObjectivesAim 2: To determine the influence of…
In oral FXa inhibitor-treated patients with acute intracranial bleeding, the objectives of this study are as follows:Primary Efficacy Objective:• To evaluate the effect of andexanet versus usual care on the rate of effective hemostasis.Secondary…
In oral FXa inhibitor-treated patients with acute intracerebral bleeding, the objectives of this study are as follows:Primary Efficacy Objective:To evaluate the effect of andexanet versus usual care on the rate of effective hemostasis.Secondary…
Primary Objective:To evaluate the efficacy of taldefgrobep alfa in participants who are already taking a stable dose of nusinersen or risdiplam or have a history of onasemnogene abeparvovec-xioi, compared to placebo, measured by change in the 32…
The purpose of this first-in-human study is to evaluate the safety, tolerability, efficacy, pharmacokinetics (PK), and pharmacodynamics (PD) of multiple ascending doses (MADs) of DYNE-101 administered intravenously (IV) to participants with DM1.…