3 results
Approved WMOCompleted
Primary objective: To determine the pharmacokinetic profile of lopinavir and ritonavir in two differ-ent co-formulations (Lopimune granules and Lopimune tablets) after single-dose in HIV-negative, healthy adult subjects, and to compare this to the…
Approved WMOCompleted
To identify the characteristics on pCLE and OCT images of the alveolar compartment in mechanically ventilated critically ill patients with non-resolving acute respiratory failure.
Approved WMOCompleted
Primary• To evaluate the safety and tolerability of AMG 199 in adult subjects• To determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) Secondary• To characterize the PK of AMG 199 • To evaluate preliminary anti-tumor…