4 results
to study the effect of pre-treatment with the specific a7nAChR agonist GTS-21 on cytokine production and the effects on the subsequent subclinical organ dysfunction in the human endotoxemia model. to measure the effect of LPS administration in the…
Aim of this study is to investigate the effects of oral administration of GTS-21 in healthy volunteers on cytokine release in ex-vivo TLR agonists stimulated whole blood . Pharmacokinetic and pharmacodynamic data will be collected with respect to…
To compare the safety and efficacy of different doses and regimens of Allocetra-OTS to that of Placebo in the treatment of organ failure in adult sepsis patients
The purpose of this study is to demonstrate improvement in Disease-Free Survival (DFS) with xevinapant compared to placebo when added to RT irrespective of subsequent anticancer therapy.