5 results
This study is aimed to determine the efficacy of varenicline in reducing EDS in PD patients.
Primary:* Evaluate the safety and tolerability of ALKS 7119 following oral administration of multiple ascending doses of ALKS 7119 in healthy male and female adultsSecondary:* Evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of ALKS 7119…
Time to recurrence of sustained VT and/or appropriate ICD therapy; ATP or shock
To characterize the multiple-dose pharmacokinetics of varenicline in adolescent maleand female smoking subjects
To evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of ALKS 7119 following oral administration of single ascending doses of ALKS 7119 in healthy male adults