5 results
The primary objectives are to investigate whether L-carnitine infusion may rescue lipid-induced insulin resistance and whether L-carnitine infusion is improving metabolic flexibility in the state of lipid-induced insulin resistance. Furthermore,…
The main objective of the study is to investigate the muscarinic cholinergic system as a biological substrate for cognitive dysfunction in schizophrenia. Since cognitive dysfunction is the most disabling and untreatable characteristic of…
CAEB071A2206 will assess safety, efficacy and target trough levels for optimal dosing of AEB071 combined with Certican in a CNI-free regimen in de novo renal transplant recipients. This study will combine the investigational drug AEB071 with an…
The primary objectives are to investigate which determinants (primarily carnitine status) determine the effect of carnitine supplementation on metabolic flexibility and insulin sensitivity in patients with type 2 diabetes. Furthermore, a secondary…
The aim of this study is to test the safety and effectiveness of the Genus Unicompartmental knee prosthesis over a period of 10 years.