4 results
Approved WMORecruiting
To assess the efficacy of AZD9291 compared to placebo as measured by disease free survival (DFS)Protocol v1.0, 4Jun2015, p30
Approved WMORecruiting
To investigate the effect of a CYP3A4 inducer (rifampicin) on the PK of AZD9291.
Approved WMORecruiting
To investigate the effect of a CYP3A4 inhibitor (itraconazole) on the PK of AZD9291.
Approved WMORecruiting
Primary objectives• To identify the percentage of patients in which a drug resistant clone can be detected with ctDNA before the emergence of radiological progression.• To determine the success rate of crizotinib and osimertinib combination…