2 results
Approved WMOCompleted
• To evaluate the tolerability and safety of ascending single oral doses of ACT-541468 in healthy male subjects.• To investigate the single oral dose pharmacokinetic (PK) and PD of ACT-541468 in healthy male subjects.• To investigate dose…
Approved WMOPending
The changes in expiratory flow limitation during increasing levels of external PEEP in COPD patients can be followed with the deltaXrs-8 using FOT.To evaluate whether the deltaXrs is good outcome parameter to determine the external PEEP level needed…