3 results
AdOpt CRT is designed to compare indices of cardiac function at device settings optimized using an investigational Adaptive CRT (aCRT)algorithm versus CRT with nominal programming. The comparison will be performed during rest and submaximal exercise…
1. Evaluate the relation between pretreatment muscle weaknesses, spasticity, abnormal synergies, and changes in viscoelastic joint properties on the one hand, and changes in upper extremity spasticity following treatment on the other hand in…
Sub-study APhase 1b:To assess the DLT rate and estimate the MTD of sasanlimab in combination with encorafenib and binimetinib to determine the RP2D for the combination. Phase 2:To assess the durable ORR of sasanlimab in combination with encorafenib…