3 results
Demonstrate the safety and efficacy of ventilation with Ventrain® during 5 minutes. Safety is demonstrated if the peak pressure during insufflation does not exceed 25 cm H2O and PEEP (Positive End Expiratory Pressure) is not smaller than -5 cm H2O…
To determine if EBUS / EUS-B guided nodal/lung tumor sampling with 22 Gauge (G) TBNB (Acquire**) needles results in improved tissue core sample acquisition in comparison to standard 22 G TBNA needles for the diagnosis and staging of lung cancer.
Primary Objective:Part 1:- To determine the MTD and recommended phase 2 dose (RP2D) of avapritinib.- To determine the safety and tolerability of avapritinib.Part 2:* To determine the overall response rate (ORR) by RECIST criteria at the MTD/RP2D of…