8 results
Primary Objective: The primary objective of this study is to compare postoperative decentration of the FEMTIS-IOL versus a standard monofocal IOL (Acrysof monofocal IOL)Secondary Objective(s): The secondary objectives of this study are to compare:-…
To determine the influence of esomeprazole on the AUC of regorafenib in patients with mCRC or GIST.
To evaluate efficacy and safety of regorafenib in patients with metastatic colorectal cancer (CRC) who have progressed after standard therapies.The primary efficacy endpoint of this study is * Overall survivalThe secondary efficacy endpoints of this…
The objective of this study is to evaluate efficacy and safety of regorafenib in patients with HCC who have progressed after sorafenib.
Primary objectives* To assess the tolerability of regorafenib combined with paclitaxel.Secondary objectives* To assess the effect of regorafenib on uptake of paclitaxel in OGC metastases.* To assess the effect of regorafenib on regorafenib targets…
This protocol is designed to determine the safety, tolerability, and efficacy of SGI-110 in combination with irinotecan in previously treated patients with metastatic colorectal cancer who progressed on irinotecan.
Primary Objective:* The primary objective is to demonstrate the efficacy of avapritinib based on progression-free survival (PFS) determined by central radiological assessment per modified Response Evaluation Criteria in Solid Tumors (mRECIST),…
The main objective is to compare the accuracy of polyp size measurement by AccuMeasure to biopsy forceps assisted measurement. Secondary objectives are to assess: Reproducibility, precision of the measurements, time needed for measurement and…