3 results
Approved WMOCompleted
Primary Objective: To elucidate the effect of age on the UGT activities using the plasma paracetamol to APAP-glucuronide clearance after a simultaneous intravenous therapeutic dose and an oral microdose.Secondary Objectives:To determine the effect…
Approved WMORecruiting
To evaluate the efficacy of PTC857 in reducing disease progression in subjects with amyotrophic lateral sclerosis (ALS)
Approved WMOCompleted
To determine the safety, tolerability and pharmacokinetics of an 18-hour i.v. infusion of CLR325 in stable heart failure patients.