6 results
The primary objective of this study is to obtain clinical proof of principle that the addition of a PgP/BCRP inhibitor increases CNS concentrations of tyrosine kinase inhibitors by inhibition of drug efflux transporter function in the blood brain…
To investigate the effect of late onset depression and inflammation on the pathological progression from MCI to Alzheimer*s disease by determining the correlation of microglia cell activation, β-amyloid deposition, brain volume, peripheral…
To determine the pharmacokinetic properties of a new elacridar formulation
What is the prevalence of gastro-intestinal disorders and which are the determinants?
The aim of this study is to determine NET availability in patients with neurodegenerative diseases to characterize NA system degeneration in people with Alzheimer's disease, Parkinson's disease (with and without dementia) and with…
The aim of this study will be to evaluate the applicability of using CCE in the Dutch colorectal cancer screening programme in participants with positive FIT outcomes who have contra-indications for subsequent colonoscopy, who have a prior…