4 results
The effectiveness an cost effectiveness of PPIs compared to standard phlebotomy therapy in the prevention of iron overload in patients with hereditary hemochromatosis.
To study the influence of omeprazole and pantoprazole on the platelet reactivity index and the inhibition of platelet aggregation by clopidogrel.
To assess uptake of 11C-osimertinib in tumor lesions of T790M double positive patients and T790M double negative patients, thereby evaluating specific and aspecific (off-target) 11C-osimertinib accumulation in tumor tissue.
Primary:- To evaluate the safety and tolerability of repeat doses of GSK2831781 during the Induction Phase.- To characterise the efficacy dose-response of GSK2831781 during the Induction Phase.Secondary:- To evaluate the safety and tolerability of…