5 results
With an one-off infusion of anti-thymocyte globulin (ATG) during the operation the T-cell function is decreased. With this action we try to achieve that DGF does not occur or that the length of the DGF is as short as possible and less frequent…
Patients will be evaluated for safety and tolerability of the therapy, but also for signs of clinical efficacy. As long as the patients are on the ICU, measurements of clinical signs and laboratory data will be collected for safety reasons and for…
Primary Objective:1. To assess the safety and tolerability of single escalating doses of Adrecizumab in healthy male volunteers during experimental endotoxemia.Secondary Objectives:2. To determine the pharmacokinetics of single escalating doses of…
To assess the safety, tolerability and pharmacokinetic/-dynamic response, of single escalating doses of ADRECIZUMAB (0.5 mg/kg, 2mg/kg and 8 mg/kg administered as single infusion over 1 hour) in healthy male subjects.
Primary Objective: To investigate whether population screening for increased albuminuria among the Dutch population can contribute to the early detection of yet undiagnosed risk factors for renal and cardiovascular diseases in an early stage. For…