6 results
Primary Objective: - to study the influence of administration aprepitant (Emend ®) on the clearance of fentanyl, in patients using a stable dose of the fentanyl patch (Durogesic ®).Stable dose is defined as using the same dose of fentanyl during at…
To investigate the therapeutic efficacy and feasibility of hyperbaric oxygen (HBO) in addition to standard wound care in patients with pyoderma gangrenosum wounds.
Primary Objective: Major amputation rate after 12-months of follow-upSecondary Objectives: - Amputation-free survival- Health-related quality of life- Complete wound healing- Pain scores- Need for additional (vascular) interventions- Cost-…
The goal of the studies is multiple:1. To describe the pharmacokinetics of intravenously administered fentanyl and sufentanil;2. To describe the pharmacodynamics of intravenously administered fentanyl and sufentanil (important model parameters…
There are two main objectives for this study. First, we will investigate the following hypothesis: Fentanyl patches provide reduction of dyspnea compared to placebo, comparable to morphine, and with less side effects than morphine. Secondly, with…
Migration in Total Hip Arthroplasty with a Cemented BiMobile cup: Better stability with more cement?
The main objective of this study is to compare the (early) migration of the cemented BiMobile cup at two year post-surgery between 2 different cup sizes after standard optimal reaming, and therefore adjusting the amount of cement into 2 or 4…