4 results
Primary objective: Safety.Secondary objective: Efficacy.
I) Is the infusion of crystalloid fluids in healthy subjects associated with a reduction in microcirculatory perfused vessel density and increase in perfused boundary region? II) Does colloid administration attenuates the crystalloid-induced…
Primary To evaluate the treatment effect of pasireotide s.c. on plasma glucose levels during GTT at the end of s.c. dose escalation phase.Secondary: Pulse rate, hematocrit, insulin, glucagon, GLP-1 and GIP secretion during GTT at the end of s.c.…
The purpose of this study, is to evaluate the efficacy and safety of pasireotide alone or in combination with cabergoline in patients with Cushing*s disease as measured by the proportion of patients achieving normal UFC at the end of the study…