7 results
to investigate the effect and efficacy of pyridostigmine on muscle strength and fatiquabillity in patients with SMA.
The aim of this study is to investigate the immune response to a tetravalent MenACWY-TT vaccine in 10-, 12- and 15-year old children primed with the monovalent MenC-TT conjugate vaccine at a young age and to1. determine whether the MenC-specific…
To determine effect of early (re) vaccinations after the current intensive chemotherapy for ALL. We will determine if there is a difference in respons to conjugated (T cell dependent) and polysaccharide (T cell independent) vaccines. This may result…
Primary outcome:The effect of Pyridostigmine (cholinesterase inhibitor) on inflammatory signs as pain, temperature and swelling of the extremity measured according to TREND protocol (appendix 1).Pain is measured according to VAS scale, temperature,…
Primary Objective * To demonstrate the efficacy of tofactitinib in inducing remission in subjects with moderately to severely active UC. Secondary Objectives * To evaluate the safety and tolerability of tofactitinib in subjects with moderately to…
The main purpose of this study is to determine the appropriate age (10, 12 or 15 years) for a second MenC conjugate (MenCC) vaccine immunization in Dutch children that received a primary MenCC vaccination at a young age. A conclusion will be based…
Main: To assess the effect of an early extra measles immunization between 6and 12 months of age on the development of humoral and cell-mediatedimmunity against measles following routine MMR immunization at 14months of age.Secundary:Determine effect…