2 results
Approved WMOCompleted
To investigate the pharmacokinetic profile of a single dose of tacrolimus;o Whole blood concentrationso Cellular concentrations (T cells and/or PBMCs)o Relationship between whole blood and cellular concentrationsTo investigate the pharmacodynamic…
Approved WMOCompleted
Primary Objective:* To evaluate ORR of avelumab in combination with talazoparib, in patients with locally advanced or metastatic solid tumors harboring BRCA1, BRCA2 or ATM defect.Secondary Objective:* To assess the overall safety and tolerability of…