4 results
Primary Objective:Part A:To evaluate the efficacy of losmapimod for the treatment of FSHD by demonstrating slowing of disease progression assessed by reachable workspace quantification of total relative surface area (RSA) Q1-Q5 with 500 g wrist…
The primary objective of this study is to evaluate the long-term safety and tolerability of ITV injections of 10 mg lampalizumab administered to patients with GA secondary to AMD as assessed by the:• Incidence and severity of ocular adverse events•…
1. Normalization of the abnormal serum TH parameters and thereby improving the clinical condition of the AHDS patients2. Observation of changes in cognitive and motor function.
Primary Objective1. To evaluate the safety and tolerability of long-term dosing of losmapimod tablets in subjects with FSHD1Secondary Objectives1. To assess target engagement of losmapimod tablets in blood and skeletal muscle over long term dosing2…