6 results
* To evaluate the long-term efficacy of FCM (using targeted ferritin levels to determine dosing) or oral iron to delay and/or reduce erythropoiesis stimulating agent (ESA) use and/or other anaemia management options in NDD-CKD subjects with iron…
Primary Objectives:• To evaluate the efficacy of intravenous (IV) FCM compared to usual care on exercise capacity.Secondary Objectives:• To evaluate the efficacy of IV FCM compared to usual care on biomarkers for iron deficiency (ID), cardiac…
The objective of this pilot study is to investigate wether:- Increased Hb levels prior to the operation can prevent blood transfusions preoperative, blood transfusions have a negative effect on the survival of cancer patients- Treatment with…
Objective 1: analyze the effect of short-term treatment with high dose glucocorticoids on vasculopathic abnormalities as measured by NCM in patients with very early SSc.Objective 2: investigate the effects of glucocorticoids on signs and symptoms of…
The primary objective is:* To evaluate RBC transfusion independence (RBC-TI) of luspatercept compared with placebo for the treatment of anemia due to IPSS-R very low, low, or intermediate risk MDS in subjects with ring sideroblasts (* 15%) who…
Primary Objectives: * to establish - which is the best treatment, MTX or baricitinib, to ensure rapid symptom relief of recent onset UA, based on clinical and patient reported outcomes from baseline to 3 months. Secondary Objective: * to establish…