14 results
The main objective of this study is to assess the efficiency of oxytocin compared to placebo as an addition to the exposure sessions in the treatment of PTSD. We hypothesize that adding oxytocin to exposure in TF-CBT produces acute changes in…
Primary Objective:In this pilot study, the authors aim is to investigate whether esketamine reduces the incidence of POD in elderly patientspresenting for noncardiac surgery.Secondary Objective(s):To examine whether esketamine has an effect on the…
To test the hypothesis that ketamine has a modulatory effect on fibromyalgia
Primary Objective: To compare ketanest induction and maintenance to etomidate induction and maintenance with midazolam and fentanyl on hemodynamic, ventilatory and endocrine parameters during the first 2h after the diagnosis of sepsis and in need of…
The primary objective is to assess the effectiveness of the administration of intranasal oxytocin in addition to Narrative Exposure therapy (NET) in reducing PTSD and co-morbid depressive symptoms in patients with chronic PTSD, compared to…
At this time, iontophoretic administration of S(+)-ketamine is a already in use as a treatment of peripheral neuropathic pain in several pain clinics In the Netherlands (including the pain clinic at the Medical Center in Alkmaar). Although this…
1.To compare the morphine sparing effect of low-dose ketamine in peroperative infusion and in post operative PCA (Morphine use)2.To compare the occurence of side effects.3.To compare the analgesic potential of the two therapies (VAS Scores)4.To…
Aims of the study:1) To obtain pharmacokinetic parameters of S(+)-ketamine;2) To study the pharmacodynamic effects of intravenous S(+)-ketamine on experimental pain;
The objectives of the study are to assess whether:(1) SNP will reduce the occurrence of psychomimetic side effects during exposure to low-dose ketamine;(2) SNP will reduce the ketamine-induced increase in blood pressure and cardiac output;(3) SNP is…
In a randomized control trial (RCT) with mothers with postpartum depressive symptoms the following main hypotheses will be tested:• Oxytocin will promote more sensitive caregiving during mother-infant interactions and while interacting with a life-…
To gain insight in the neurobiological mechanisms behind oxytocin effects on human social-emotional behaviour.
We hypothesize that perioperative ketamine will reduce cognitive decline in postoperative patients, in line with its analgesic and anti-inflammatory properties. There are no previous data available on the effect of ketamine on postoperative…
The primary outcome is the occurrence of neonatal respiratory morbidity within 24 hours after birth. Painful contractions. Progression of labour after stopping OCT. Nonreassuring fetal heart rate pattern during OCT.
The primary objective of this study is:- To assess the rates of HIV-1 infection in men who have sex with men (MSM) and transgender women (TGW) who have sex with men who are administered daily emtricitabine/tenofovir alafenamide (F/TAF) or…